ALDH5A1 Mouse mAb
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38281ES50
50 μL
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¥ 1385.00
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38281ES60
100 μL
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¥ 2385.00
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Succinate-semialdehyde dehydrogenase is an enzyme that in humans is encoded by the ALDH5A1 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD+-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter γ-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

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WB:1/500-1/1000 IHC-P:1/50-1/100
应用案例

Western

Western blot analysis of ALDH5A1 in lysates of Human liver and HepG2 using ALDH5A1 antibody.


Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human liver using ALDH5A1 antibody.High pressure and temperature Tris/EDTA (PH 9.0) used for antigen retrieval.The brown color represents the positive signal observed with ALDH5A1 antibody.


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-15到-25度
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