The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues Ted. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Western

Western blot analysis of Cyclin A2 in K562, C6, 3T3, Hela lysates using Cyclin A2 antibody.

Immunocytochemistry

Immunocytochemistry analysis of Cyclin A2(green) in Hela using Cyclin A2 antibody,and DAPI(blue)

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Cyclin A2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.