The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

Western

Western blot analysis of ALDH1L1 in Rat kidney (1), Mouse liver (2), Rat liver (3) and Mouse kidney (4) tissue lysate using ALDH1L1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded human bladder cancer tissues using ALDH1L1 antibody.

Flow

Flow Cytometry analysis of Jurkat cells using ALDH1L1 antibody (green) and negative control (red).